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LipidXplorer Wiki

News

2012-01-17 New LipidXplorer paper published

We are happy to announce the recent publication about LipidXplorers newly implemented support for precursor ion / neutral loss scanned (PIS/NLS) spectra on triple quad mass spectrometers. Now it supports the whole range of major mass spectra technologies which is used in shotgun lipidomics. Here is a link to the article: LipidXplorer: A Software for Consensual Cross-Platform Lipidomics

2012-01-13 Bug found in LipidXplorer Version 1.2.2

Attention: A bug occurred in the file lpdxGUI.pyw when spectra are converted with the option "mc.wiff". The "Thinking..." dialog won't disappear and the Debug window contains an error message with the last line saying: "NameError: global name 'rawOut' is not defined". Please use msconvert manually for conversion of *.wiff files to *.mzXML. In the next version of LipidXplorer this bug will be fixed.

2011-12-14 LipidXplorer Version 1.2.2 released

The recent version of LipidXplorer can be downloaded at LipidXplorer on Sourceforge. There can be found also an update in form of a *.zip file.

See LipidXplorer Version 1.2.2 for infos.

LipidXplorer Documentation

MFQL library

Frequently Asked Questions (FAQ)

LXMerge: A tool for merging multiple results

Get LipidXplorer

LipidXplorer is published under GPL and available here: [LipidXplorer on Sourceforge]. Check out the LipidXplorer installation instructions for help.

Articles using LipidXplorer

Herzog, R., Schwudke, D., Schuhmann, K., Sampaio, J.L., Bornstein, S.R., Schroeder, M., and Shevchenko, A. 2011. A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language. Genome Biol 12(1): R8.

Penkov S, Mende F, Zagoriy V, Erkut C, Martin R, Pässler U, Schuhmann K, Schwudke D, Gruner M, Mäntler J, Reichert-Müller T, Shevchenko A, Knölker HJ, Kurzchalia TV. 2010. Maradolipids: diacyltrehalose glycolipids specific to dauer larva in Caenorhabditis elegans. Angew Chem Int Ed Engl. 49(49):9430-5.

Graessler J, Schwudke D, Schwarz PE, Herzog R, Shevchenko A, Bornstein SR: Top-down lipidomics reveals ether lipid deficiency in blood plasma of hypertensive patients. PLoS One 2009, 4:e6261.

Contact

For any questions and suggestions please put them on the [LipidXplorer Google Group]

If you want to contribute to the Wiki please write to herzog@mpi-cbg.de or also to the google group.

Known bugs

Please check out the [LipidXplorer Google Group] to be up-to-date on found bugs.

Bug reports

Please send Bug reports directly to herzog@mpi-cbg.de

Example spectra

Example spectra for the LipidXplorer tutorial

• Spectra of E.coli acquired on the LTQ Orbitrap with different resolution settings:File:Spectra tutorial.zip

All spectra used in the LipidXplorer article

• Spectra of E.coli and bovine heart acquired on LTQ Orbitrap XL, LTQ Orbitrap Velos and ABI QStar pulsar (in DDA and MPIS mode):File:Spectra article.zip