Main Page

LipidXplorer Wiki

News

2012-06-07 New release: LipidXplorer Version 1.2.3

2012-02-15 Bug found in LipidXplorer Version 1.2.2

Attention: Another bug was found in the current version of LipidXplorer. The conversion of profile raw files with the "mc.raw profile" setting to into the LipidXplorer compatible file format produces wrong results. Please download this file (right click and save as) and copy it into your bin folder of LipidXplorer and overwrite the old file.

2012-01-17 New LipidXplorer paper published

We are happy to announce the recent publication about LipidXplorers newly implemented support for precursor ion / neutral loss scanned (PIS/NLS) spectra on triple quad mass spectrometers. Now it supports the whole range of major mass spectra technologies which is used in shotgun lipidomics. Here is a link to the article: LipidXplorer: A Software for Consensual Cross-Platform Lipidomics

2012-01-13 Bug found in LipidXplorer Version 1.2.2

Attention: A bug occurred in the file lpdxGUI.pyw when spectra are converted with the option "mc.wiff". The "Thinking..." dialog won't disappear and the Debug window contains an error message with the last line saying: "NameError: global name 'rawOut' is not defined". Please use msconvert manually for conversion of *.wiff files to *.mzXML. In the next version of LipidXplorer this bug will be fixed.

LipidXplorer Documentation

MFQL library

Troubleshooting

LXMerge: A tool for merging multiple results

Get LipidXplorer

LipidXplorer is published under GPL and available here: [LipidXplorer on Sourceforge]. Check out the LipidXplorer installation instructions for help.

Feature suggestions

LipidXplorer will be further developed all the time. If you have suggestions for useful features, please write to the LipidXplorer mailing list and we will post them here. We also will post a status report on the suggested features: the LipidXplorer wishlist.

LipidXplorer Bibliography

Estronca, LM; Silva, JC; Sampaio, JL; Shevchenko, A; Verkade, P; Vaz, AD; Vaz, WL; Vieira, OV Molecular etiology of atherogenesis - in vitro induction of lipidosis in macrophages with a new LDL model. PloS ONE 7: e34822.

Klose, C; Surma, MA; Gerl, MJ; Meyenhofer, F; Shevchenko, A; Simons, K. Flexibility of a eukaryotic lipidome - insights from yeast lipidomics. PloS ONE 7: e35063.

Kai Schuhmann, Reinaldo Almeida, Mark Baumert, Ronny Herzog, Stefan R. Bornstein, Andrej Shevchenko. Shotgun lipidomics on a LTQ Orbitrap mass spectrometer by successive switching between acquisition polarity modes JMS 2012 Jan 26. 47(1)

Ronny Herzog, Kai Schuhmann, Dominik Schwudke, Julio L. Sampaio, Stefan R. Bornstein, Michael Schroeder, Andrej Shevchenko. LipidXplorer: A Software for Consensual Cross-Platform Lipidomics PLoS ONE 7(1): e29851. doi:10.1371/journal.pone.0029851

Contact

For any questions and suggestions please put them on the [LipidXplorer Google Group]

If you do not want to join google, please write me (herzog@mpi-cbg.de) an email and I'll add you to the group.

If you want to contribute to the Wiki please write to herzog@mpi-cbg.de or also to the google group.

Known bugs

Please check out the [LipidXplorer Google Group] to be up-to-date on found bugs.

Bug reports

Please send Bug reports directly to herzog@mpi-cbg.de

Example spectra

Example spectra for the LipidXplorer tutorial

Spectra of E.coli acquired on the LTQ Orbitrap with different resolution settings:File:Spectra tutorial.zip

All spectra used in the LipidXplorer article

Spectra of E.coli and bovine heart acquired on LTQ Orbitrap XL, LTQ Orbitrap Velos and ABI QStar pulsar (in DDA and MPIS mode):File:Spectra article.zip