Difference between revisions of "LXMerge"

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==TEST==
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==Purpose of LXMerge==
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===Use case one: using specific occupation threshold settings===
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The problem is if you have samples groups coming from different sources. So, for example, one can examine different phenotypes of a particular organism. Every phenotype is analysed including biogical and technical repeats leading to groups of samples assigned to each phenotype, respectively.
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To have an accurate lipid identfication the occupation threshold option from the import settings of LipidXplorer can be used to assert that a peak is present in a given percentage of samples. The problem is, that there could be lipids which are not present in some samples, which results from the biological experiment. A occupation threshold setting for all samples would not help in this case.
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With LXMerge one can overcome this issue, although it is not as conviniend as clicking some buttons in the GUI. LXMerge merges result files coming from LipidXplorer. For this particular use case it would make sense to import every sample group in an own MasterScan with a stringend occupation threshold setting and merge the results.

Revision as of 13:03, 7 October 2010

Purpose of LXMerge

Use case one: using specific occupation threshold settings

The problem is if you have samples groups coming from different sources. So, for example, one can examine different phenotypes of a particular organism. Every phenotype is analysed including biogical and technical repeats leading to groups of samples assigned to each phenotype, respectively.

To have an accurate lipid identfication the occupation threshold option from the import settings of LipidXplorer can be used to assert that a peak is present in a given percentage of samples. The problem is, that there could be lipids which are not present in some samples, which results from the biological experiment. A occupation threshold setting for all samples would not help in this case.

With LXMerge one can overcome this issue, although it is not as conviniend as clicking some buttons in the GUI. LXMerge merges result files coming from LipidXplorer. For this particular use case it would make sense to import every sample group in an own MasterScan with a stringend occupation threshold setting and merge the results.